Thank you, Top Rank, and especially Bob Arum, for giving me this opportunity and letting me show and prove in the ring my ability to fight as a professional."

Top Rank's vice president Carl Moretti announced that Gaibnazarov would make his debut as a lightweight at the StubHub Center in Carson, California on 22 April in an 8-round bout.

[4][5] Gaibnazarov's next fight took place 29 days later on the Terence Crawford vs. Félix Díaz undercard at Madison Square Garden in New York City against Agustine Mauras.

[6] Gaibnazarov next appeared at the Convention Center in Tucson, Arizona on 22 September 2017 against Mexican boxer Victor Rosas (9-6, 3 KOs).

Gaibnazarov applied pressure, landing clean shots, however was unable to stop Rosas, winning the bout on all three scorecards 80–72 to remain undefeated.

[7] On 12 October it was announced that he would appear on the undercard of Vasiliy Lomachenko vs. Guillermo Rigondeaux on 9 December at the Madison Square Garden Theater in New York City.

[10] Gaibnarazov's fifth professional fight was set to take place at Lakefront Arena in New Orleans on 14 July 2018 against fellow undefeated American boxer Kevin Johnson (5-0, 4 KOs) in a scheduled 8-round bout.

[15] In February 2019, Top Rank announced the rematch of Miguel Berchelt vs. Francisco Vargas, which was to take place at the Tucson Arena in Arizona on 11 May 2019.

The undercard was announced on 1 May, with Gaibnazarov headlining the ESPN+ preliminary card, stepping up in competition against 23 year old Mykal "The Professor" Fox (19-1, 5 KOs) in a 10-round super lightweight contest.

[22] His next bout came a year later on 5 December 2020, making his debut in Russia against Manuk Dilanyan (11-4-1, 4 KOs) at the RCC Boxing Academy, Yekaterinburg.

[23][24] His next bout came 20 months later, fighting in his home country for the first time as a professional at the Humo Arena in Tashkent, defeating 39 year old Jaider Parra by knockout after just 38 seconds of round 1.

[25] He returned to the same arena on 2 December 2022, this time fighting fellow countryman Jamshid Karimov in a 10-round light middleweight bout.

[26] Gaibnazarov's next fight was scheduled to take place on 6 November 2023 against Russian boxer Radzhab Butaev (14-1, 11 KOs) at the Red Arena in Krasnaya Polyana.