The works he produced in the early years of his career were naturalistic in style, but after 1910 the influence of the symbolists and particularly of Gustav Klimt turned him toward a more visionary approach.

[4] Often working in tempera, Casorati drew inspiration from his study of Renaissance masters, especially Piero della Francesca, as in his 1922 portrait entitled Silvana Cenni.

[6] Casorati himself wrote, in 1931: "In taking up, against me, the old polemic of classicism and romanticism, people rail against intellectualized and scholastic order, accuse my art of being insincere, and wilfully academic—in a word, of being neoclassical.

... since my art is born, so to speak, from within, and never has its source in changing "impressions", it is quite natural that ... static forms, and not the fluid images of passion, should be reflected in my works".

Beginning in 1923, he opened his studio to the young art students of Turin,[3] and to emerging Italian artists such as Quinto Martini and painters of the Gruppo dei Sei (Group of Six).

Most of Casorati's important works are in Italian collections, public and private, including the Modern Art Revoltella Museum in Trieste and Galleria Nazionale d'Arte Moderna.