Rose has amassed over 150 film credits, and is best known for her work in the horror genre, for which she is recognized as a "scream queen".

Her other horror roles include Elsa Lansing in Silent Night, Zombie Night (2009), Mother in The Perfect House (2012), Rachel Steele in Camp Dread (2014), Angela Freeman in Death House (2018), Kathleen in Victor Crowley (2018), Ms. Crowell in Bloody Summer Camp (2022), and Ms. Principe in Terrifier 2 (2022).

[2] Felissa Rose Esposito was born on May 23, 1969 in Greenwich Village in New York City and raised in Syosset on Long Island.

[8] In addition Felissa co-hosted the 2005 Village Halloween Parade in New York City with fellow scream queens Debbie Rochon and Raine Brown.

[11] Rose starred in a role as Mother in the segment "Dinner Guest" in the anthology horror film, The Perfect House.

[13] In 2016, Felissa starred in the paranormal horror film Family Possessions, written and directed by Tommy Faircloth.

Rose and Miller were co-stars in Dave Campfield's 2008 horror comedy Caesar and Otto's Summer Camp Massacre.