Femme Osage is an unincorporated community in southwest St. Charles County, in the U.S. state of Missouri.
[1] The community is on Missouri Route T along the bank of the Femme Osage Creek.
[2] A post office Femme Osage was in operation from 1816 until 1933.
[3] The community takes its name from nearby Femme Osage Creek.
This St. Charles County, Missouri state location article is a stub.