Josephville is a village in St. Charles County, Missouri, United States.

A post office called Josephville opened in 1875, and remained in operation until 1910.

[5] According to the United States Census Bureau, the village has a total area of 2.38 square miles (6.16 km2), all land.

12.0% of all households were made up of individuals, and 5.3% had someone living alone who was 65 years of age or older.

19.8% of all households were made up of individuals, and 3.3% had someone living alone who was 65 years of age or older.

About 4.5% of families and 1.8% of the population were below the poverty line, including 1.8% of those under the age of eighteen and none of those 65 or over.