[3] Fencamfamin is still used, though rarely, for treating depressive day-time fatigue, lack of concentration and lethargy, particularly in individuals who have chronic medical conditions, as its favourable safety profile makes it the most suitable drug in some cases.

[4] Not to be used with heart diseases, angina pectoris and decompensated cardiac insufficiency, glaucoma, hyper-excitability and thyrotoxicosis or while treated with monoamine oxidase inhibitors.

[4] In a study on slices of rat corpus striatum and substantia nigra fencamfamin acted as an indirect dopamine agonist.

It released dopamine by a similar mechanism to amphetamines, but was ten times less potent than dexamphetamine at producing this effect.

It was concluded that, at least in the models employed, the in vitro profile of fencamfamin is more similar to that of nomifensine, a reportedly pure uptake inhibitor, than to d-amphetamine.

[10] The reduction of both functional groups can also be achieved simultaneously by the use of Raney nickel,[10] and this transformation has recently been optimized by Russian chemists.

Although the isomeric composition of the Diels-Alder adduct itself does not seem to have been determined, Poos et al. reported a ratio of ~3:1 for the saturated un-ethylated amine derived from it.