Ferdinand G. "Fritz" Holtkamp (c. 1889 – 1944) was an American college football and college basketball coach] He served as the head football coach at Mississippi Agricultural & Mechanical College—now known as Mississippi State University—from 1920 to 1921 and Western Reserve University—now a part of Case Western Reserve University—from 1922 to 1925, compiling a career college football coaching record of 25–26–3.

Holtkamp played college football at Ohio State University as a center from 1916 to 1919.

He died in 1944 at the age of 55 at Pearl Harbor following a long illness.

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