The comune, located in the valley of the Nera, is divided by the river into the burghs of Matterella and Precetto.
Remains of ancient settlements include an Etruscan necropolis outside Ferentillo, at Caldane.
The town developed around a 14th castle (Castello di Madonna), first owned by the Monaldeschi della Cervara, then of the Spada and the Dukes of Montevecchio.
The biggest fraction is Macenano where the San Pietro in Valle Abbey is located.
Other fractions are: Umbriano, Ampognano, Castellonalto, Castellone Basso, Colle Olivo, Colli, Gabbio, Leazzano, Le Mura, Lorino, Macchialunga, Macelletto, Macenano, Terria, Monterivoso, Nicciano, Sambucheto, San Mamiliano.