San Venanzo is a comune (municipality) in the Province of Terni in the Italian region Umbria, located about 30 km (19 mi) southwest of Perugia and about 45 km (28 mi) northwest of Terni.

San Venanzo borders the following municipalities: Ficulle, Fratta Todina, Marsciano, Monte Castello di Vibio, Montegabbione, Orvieto, Parrano, Piegaro, Todi.

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