Ferentino Cathedral (Italian: Duomo di Ferentino; Basilica Cattedrale dei Santi Giovanni e Paolo) is a Romanesque Roman Catholic cathedral in the town of Ferentino, Lazio, Italy, dedicated to Saints John and Paul, 2nd-century martyrs from Rome.
The present cathedral stands on the site of the town's ancient acropolis.
It was founded by Pope Paschal I in the early 9th century over the remains of a Roman temple.
The cathedral still contains some elements of the 9th-century church and 12th-century mosaics from the studio of the Cosmati.
The cathedral also has a 16th-century silver equestrian statue of Saint Ambrose by the jeweller Fantino Taglietti and two 16th-century silver busts of Saints Peter and Paul attributed to followers of Benvenuto Cellini.