After graduating he practised law and is not known to have written any further literary works, although La Celestina achieved widespread success during his lifetime.

Despite difficulties with the Inquisition, Rojas was a successful lawyer and became mayor of Talavera de la Reina, where he lived for the last three decades of his life.

[2] While at the university he began writing La Celestina (originally titled Tragicomedia de Calisto y Melibea), which was published in 1499.

[6] On returning to the family home after leaving the university Rojas found his relations under scrutiny from the Inquisition; he himself was never suspected of Judaism.

[2] The writer Gordon Campbell observes that during Rojas's lifetime La Celestina achieved rapid success: "in the course of the sixteenth century some 60 editions and six sequels were published.