[2] It was an evolution over the preceding Ferrari 212 Export with important engine upgrades that greatly improved power output.

The V12 engine received a slightly larger total displacement, due to a bigger bore.

The engine improvements consisted of an innovative and more efficient intake manifold design and an upgraded distribution system.

Some were even of a 166 MM ancestry like the s/n 0152EL,[9] the very first 225 S.[1] Fourteen open spyder cars were created, bodied by Vignale to a Giovanni Michelotti design.

The s/n 0176ED, commissioned by Antonio Stagnoli, also featured small inboard headlights and an outside spare wheel flush with the rear trunk.

The internal measurements were now 70 by 58.8 mm (2.8 by 2.3 in) of bore and stroke and the resulting total capacity was 2,715.46 cc (2.7 L; 165.7 cu in).

[1] The front suspension was independent with double wishbones, transverse leaf spring and hydraulic shock absorbers.

The rear consisted of a live axle with twin semi-elliptical springs and hydraulic shock absorbers.

Few select examples received a smaller diameter tubular trellis-frame with additional truss-type cross-braces.

This design was introduced on a 1951 Ferrari 212 Inter Touring Berlinetta, s/n 0141ET, that was used in competition by "Pagnibon" (Pierre Boncompagni) and was later offered for the 212 Export and 225 S ranges.

The best score was a fifth place overall and a win in class by Eugenio Castellotti and Annibale Broglia in an only Touring Barchetta s/n 0166ED, entered by Scuderia Guastella,[12] followed by another 225 S Vignale driven by Franco Bordoni.

[16][19] Later the same year, at the 12 Hours of Casablanca race, Jean Lucas with Jacques Péron achieved a second place, only a lap behind the winning Talbot-Lago T26GS.

[20] Later, Bruno Sterzi and Arnoldo Roselli scored a victory at the Coppa della Toscana in a Vignale Berlinetta s/n 0178ED.

[21][22] For the 1952 Monaco Grand Prix for sports cars, Ferrari had entered no less than six 225 S', out of twenty participants.

After 100 laps, Vittorio Marzotto was the winner, followed by Eugenio Castellotti, Stagnoli / Biondetti, Jean Lucas and "Pagnibon".

[27] Later, Jean Luca scored another victory at the Circuit de Bressuire in the same berlinetta he drove at Casablanca.

A "Tuboscocca" Vignale Spyder, s/n 0194ET, driven by Tom Cole finished eleventh overall and fourth in class.

[21][32] In September 1952, the second edition of the Tour de France marathon was contested by "Pagnibon" and Adolfo Macchieraldo.

[25] After 1953, the Ferrari 225 S was campaigned on various race tracks with many accomplishments in the US, Argentina, Brazil, Portugal and Italy till 1959.

Beautiful design, racing pedigree, limited production numbers and marque's heritage.

[43] At the 2020 Elkhart Collection auction by RM Sotheby's, the 1952 Ferrari 225 S Vignale Berlinetta that entered both Mille Miglia and 12 hours of Casablanca, will be offered for sale at an estimate of US$2.5–3 million.