It was the first in the long lineage of Ferrari 250 road and race cars powered by a ubiquitous 3.0-litre Colombo V12 engine.

[9] The power output benefited from an updated and innovative design of the intake and distribution, already introduced on the 225 S, and was now at 230 PS (169 kW; 227 hp) at 7500 rpm.

The resulting trellis space frame was slightly lighter and more rigid than the standard tubular chassis.

[10] It was developed by Gilco, a chassis specialist company established by Gilberto Colombo, and first introduced on a late 212 Export.

The front suspension was independent with unequal-length wishbones and transverse leaf springs, aided by hydraulic shock absorbers.

[11] After a magnificent performance on the Futa and Raticosa passes, they managed to finish first overall, continuing Ferrari's dominance in this road marathon.

[4][12] Alberto Ascari and Luigi Villoresi were chosen by Scuderia Ferrari to compete in the 1952 24 Hours of Le Mans in the 'Sport 3.0' category.

Later the same year, at the Coppa Acerbo for sports cars, renamed as the 12 Hours of Pescara, yielded another success for Ferrari.

Still in 1953, at the Giro di Sicilia, Franco Cornacchia and Gino Bronzoni finished the race prematurely with a broken differential.

The car competed in the GP Monza, entered by Scuderia Guastalla, finishing at an eighth place.