[1] Following his graduation he continued to write for various publications, including Resimli Gazete and Son Telgraf which was started by him and Sadri Ethem, Hüseyin Avni, Suphi Nuri İleri in 1924.
[1] Due to his opposition to the Republican People's Party (CHP) and the regime he was tried at the Independence Tribunal of Elazığ for three months and was found not guilty on 13 September 1925.
[2][3] Karaosmanoğlu continued to criticize the single-party government through his articles in Vatan during the World War II period.
[1] He was dismissed from the DP in October 1955 as a result the conflicts between him and Prime Minister Adnan Menderes.
[6] Karaosmanoğlu had been criticizing both Menderes and President Celâl Bayar due their "dictatorial tendencies".
[6] Karaosmanoğlu and other former DP politicians established the Liberty Party, and he was elected as its chairman on 22 December 1955.
[8] The other signatories of the statement included İsmet İnönü, Turgut Göle, Fuat Arna, Kasım Gülek, Enver Güreli, Ahmet Bilgin, İbrahim Öktem and Nurettin Ardıçoğlu.
[8] Karaosmanoğlu was a deputy candidate for the party from Istanbul in the 1957 general election, but he did not win a seat.