Its comics division was best known for its pinup-style good girl art, as epitomized by the company's most popular character, Sheena, Queen of the Jungle.

[2] At the end of 1929, a New York Times article referred to John B. Kelly as "head" of Fiction House, Inc., and a new location of 271 Madison Avenue.

Fiction House occasionally acquired other publishers' magazines, such as its 1929 acquisition of Frontier Stories from Doubleday, Doran & Co.[9] By the 1930s, the company had expanded into detective mysteries.

By the late 1930s, publisher Thurman T. Scott expanded Fiction House into comic books, an emerging medium that began to seem a viable adjunct to the fading pulps.

[11] Other features in Jumbo Comics #1 included three by future industry legend Jack Kirby, representing his first comic-book work following his debut in Wild Boy Magazine:[12] the science fiction feature The Diary of Dr. Hayward (under the pseudonym "Curt Davis"), the modern-West crimefighter strip Wilton of the West (as "Fred Sande"), and Part One of the swashbuckling serialization of Alexandre Dumas, père's The Count of Monte Cristo (as "Jack Curtiss"), each four pages long.

Guns blazing, daggers unsheathed, sword in hand, they leaped across the pages, ready to take on any villain.

A subsequent, wide-ranging investigation by the Senate Subcommittee on Juvenile Delinquency, coupled with outcry by parents, a downturn in comics sales, the demise of the pulps, and the rise of television and paperback novels competing for readers and leisure time, Fiction House faced an increasingly difficult business environment, and soon closed shop.