The elevator indicator panel and mailbox in the lobby are in an integrated design which resembles the building's exterior shape.

The entrances on the east and west facades rise the entire height of the base and are also framed in black granite.

Five pilasters faced in white Yule marble separate the bays containing revolving doors that provide access to the lobby.

The upper stories are sheathed in limestone with windows grouped vertically and recessed to emphasize the building's height.

The world's first skyscraper, the Home Insurance Building (1885-1931), occupied the western portion facing LaSalle and Adams Streets.

The 43rd and 44th floors house executive dining rooms for use by the bank and selected other tenants, with a cafeteria located on the concourse level.