In 2004, Xie ran with Jeanette Aw, Joyce Chao and Felicia Chin, dressed only in bikinis, along Orchard Road for the Channel 8 drama The Champion.
In 2006, Xie attempted her first villain role as a spoilt diamond heiress in the Channel 8 drama An Enchanted Life, starring alongside Yvonne Lim and Pierre Png.
She played a calafare (a Singaporean slang term for a background actor or extra) named Joleen Wee, a wannabe singer who actually cannot sing, and often spouts phrases like "eyes wide open", "laugh out loud" and so on.
Although the exact reason behind her pulling out of the series was never revealed, several colleagues hinted to the media that Xie had expressed discomfort in taking up this role before filming commenced.
She then hosted a variety show, Lodge with Me (我行我宿), which aired in May 2010, alongside Felicia Chin, Rui En, and Zhou Ying.
After a 7-year hiatus, she returned to Singapore to film Left Behind, a 2016 MediaCorp series, in which Xie plays a psychiatrist, about which she said the role's tribulations were a personal reflection of her own life in previous years.
[5][6] In various media interviews, Xie was cited as saying she wanted to spend more time with her family, especially with one of her cousins who was critically ill, as one major reason for returning to Singapore.
[7] In 2018, Xie landed a role in the Warner Bros. film Crazy Rich Asians, starring Constance Wu and Henry Golding.
Xie starred alongside Elvin Ng, Zhang Yaodong, Tong Bingyu, and Dawn Yeoh in Gifted, a crime thriller filmed in Malaysia.
In 2012, Xie helped to launch the Shanghai outlet of local fashion boutique Surrender, where she also spearheaded a collaboration between Japanese accessories brand Ambush and South Korean rapper G-Dragon.
[9] Prior to her stint in Shanghai, Xie had spent a year living in Japan and worked as a producer for Polish documentary filmmaker and photographer Tomasz Gudzowaty.