Metropolitan Macarius was apparently injured in the fire when the Cathedral of the Dormition in the Kremlin was threatened by the flames and the metropolitan was taken out through a breach in the Kremlin walls and let down by rope into the Moscow River.
[3] The Muscovites put the blame on the tsar's maternal relatives from the Glinski family [ru].
A rebellion began and Yuri Glinski was stoned to death inside the Cathedral of the Dormition in front of a horrified Metropolitan Macarius.
Yuri's brother, Mikhail Glinski attempted to flee to Lithuania but failed, and his mother, Anna Glinskaya – the tsar's grandmother – was accused of using sorcery to start the fire.
[4] The rebellion resulted in the fall of the Glinski party and eventually strengthened the positions of the young tsar, although he did not hand his grandmother over to the mob as they demanded.