Duval County property appraiser states it's Campus size is 317,321 sqft.

The school is built around a large paved courtyard, reminiscent of Spanish architecture from the colonial period of Latin America.

In 2006, an additional wing was added to the school, to accommodate the explosive growth in North Jacksonville.

As of the 2018–19 school year, First Coast High School had an enrollment of 1,991 and 94 classroom teachers (on an FTE basis), for a student-teacher ratio of 21:1.

[citation needed] The educational partnership, funded by the Bill & Melinda Gates Foundation, was designed to raise the school's graduation rate and improve college readiness, especially among minority and low income students.