The Iroquois Nationals men's lacrosse team was formed and sanctioned by the Grand Council of the Haudenosaunee in 1983 in preparation of friendlies at the NCAA championship in Baltimore, Maryland.

Prior to the 1984 Summer Olympics, the Nationals held the Jim Thorpe Memorial Games and Pow-Wow, a 6-team event with local and international teams in Los Angeles.

The company is to develop programs to "promote wellness-and-fitness activities in Native American communities throughout the region", and team members may go to speak to local groups.

Team members will also assist in testing of sustainable produced sportswear for Nike's research and development of processes to use non-toxic dyes and biodegradable organic cotton.

The event took place on Haudenosaunee Territories at Tsha’Hon’nonyen’dakhwa’ Onondaga Nation Arena and the Carrier Dome near Syracuse, as well as the First Niagara Center in Buffalo September 18–27, 2015.