It is a stop on the MBTA Commuter Rail Fitchburg Line and a hub for Montachusett Regional Transit Authority local and intercity bus routes.

[2]: 87  The Vermont and Massachusetts Railroad (V&M) soon extended the line west of Fitchburg, reaching Baldwinville in September 1847 and Greenfield on January 20, 1850.

[2]: 87  The Cheshire Railroad opened in stages from South Ashburnham beginning in 1847; Fitchburg was the first major station to the east of the junction.

[3] Fitchburg was a major station for B&M intercity trains - including the Green Mountain Flyer and Mount Royal on the Cheshire Branch, and Minuteman on the Boston–Troy mainline.

[8] The still-extant 1980 station - a short stretch of bare asphalt with a bus shelter - was replaced by the Fitchburg Intermodal Transportation Center on May 15, 2000.