Much of the school was subsequently destroyed by incendiary bombs in the Cardiff Blitz[3] during the night of 3–4 March 1941 in World War II.

The Howard Gardens site was to be re-developed (as Cardiff School of Art & Design) and Fitzalan Technical High School acquired new premises on the present site in Lawrenny Avenue, Canton, Cardiff which were opened on Tuesday 3 March 1964.

Pupils with special educational needs receive specialist support in class to ensure that they can access the curriculum fully.

[9] The school campus includes two gymnasia, a multi use dance studio, two indoor multi-use halls, two fitness suites, a sports hall, a swimming pool, four grass football and rugby pitches and an artificial cricket square.

In January 2020 a class of fifteen to sixteen-year-olds, who had had the same maths teacher since they started the school in year 7, all passed their mathematics GCSE six months ahead of schedule and all achieved A*, the top grade.

The achievement was widely reported in the British, Cameroonian and international media with the teacher Francis Elive described as 'The Maths Whisperer'.