The Fitzwilliam Strait (76°30′N 116°0′W / 76.500°N 116.000°W / 76.500; -116.000) is a natural waterway through the central Canadian Arctic Archipelago in the Northwest Territories of Canada.
It separates Prince Patrick Island (to the north-west), Melville Island (to the south-east) and Emerald Isle (to the north-east).
It opens into the Kellett Strait to the south-west.
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