From its opening in October 2017, FivePoint Amphitheatre served as one of Orange County's major outdoor concert venues with many musicians, bands, and performers making tour stops there.

In early 2017, Live Nation partnered with Great Park developer FivePoint to establish a temporary venue on its property by the end of the year.

[3] The amphitheatre was originally scheduled to open on August 26 with local bands Young the Giant and Cold War Kids, but the inaugural concert was postponed to October 5.

[5] On October 21, 2023, Live Nation announced the FivePoint Amphitheatre would permanently close after the Zac Brown Band event of the same night.

The city of Irvine ended its partnership with Live Nation to rule out any future development and negotiations in July 2023, citing the proposed size of the venue, noise, and safety concerns.