Flacherie infected silkworms look weak and can die from this disease.
Silkworm larvae that are about to die from flacherie are a dark brown.
This either alone or in combination with bacterial infection destroys the gut tissue.
Bacterial pathogens contributing to infectious flaccherie are Serratia marcescens, and species of Streptococcus and Staphylococcus in the form known as thatte roga.
In the nineteenth century, flacherie resisted the efforts of Louis Pasteur.