The lobe is involved in maintaining posture and balance as well as coordinating head-eye movements.

[1] The lobe is functionally associated with the vestibular system and is therefore also referred to as the vestibulocerebellum.

[1] The lobe in turn projects efferents back to the vestibular nuclei which in turn give rise or project to: the lateral vestibulospinal tracts which maintain posture and balance by regulating tone of the axial and proximal limb extensor mucles (i.e. the antigravity muscles); the medial vestibulospinal tracts which regulate the tone of neck muscles; and the medial longitudinal fasciculi which coordinates head-eye movements (vestibuloocular reflex).

Efferents of the lobe are the cerebellovestibular fibers which project to the vestibular nuclei.

[2] The most common cause of damage to the flocculonodular lobe is medulloblastoma in childhood.