Flora Stone Mather (April 8, 1852 – January 19, 1909) was a prominent philanthropist and advocate supporting religious, social welfare, and educational institutions in Cleveland, Ohio.

In 1881 Flora married Samuel Livingston Mather, a wealthy businessman with shipping and mining interests in the Great Lakes region.

Her engagement with these organizations often went well beyond financial support, involving her in direct service and advocacy for broader charitable investment in the work.

Together, Flora and Clara continued their parents’ tradition of civic generosity, earning their own recognition as prominent philanthropists.

Flora Mather's most enduring philanthropic legacy is woven deeply into Case Western Reserve University's past and present.

Amasa Stone, her father, was instrumental in moving Western Reserve College from Hudson, Ohio to Cleveland in 1882.

Flora Stone Mather died on January 19, 1909, at ‘Shoreby’, the family's home on the Lake Erie shore in Bratenahl near downtown Cleveland.