The town was established in 1899 by the Georgia Southern and Florida Railway.

Streets north and south are named for trees or shrubs.

Florahome was also once an island and was drained of all its water to make way for crops, animals, and homes.

The town is built upon a sandy hill rising from the swampy areas.

Florahome has a specific zip code (32140), which covers an area of 43.24 square miles and claimed a population of 1,471 according to the 2010 census.