Florence is an unincorporated community in Paint Township, Madison County, Ohio, United States.

It is located along U.S. Route 42 between London and South Charleston.

[2] Florence was never platted; the community simply grew around a station built on the Pennsylvania Railroad.

[3] As of 1915, the community contained one grain elevator, one general store, the railroad station and freight depot, and only a few houses.

This Madison County, Ohio state location article is a stub.