[3] Florence County is part of the Iron Mountain, MI–WI Micropolitan Statistical Area.

The first white man to document his journey through Florence County was Thomas J. Cram, who surveyed northeast Wisconsin in 1840 and 1841.

The region belonged to the Menominee tribe, who mingled with the Chippewa there.

In 1879, Fisher named the mine and town after the wife of Nelson Powell Hulst, Florence Terry Hulst, establishing the name for the county as well.

[13] Additionally, there were fewer than five reported induced abortions performed on women of Florence County residence in 2017.

Florence County has voted for the Republican presidential candidate in every election since 1996.