[5] Her sixth form education was at Mfantsipim School at Cape Coast in the Central Region of Ghana.
[4] Dolphyne entered the University of Ghana in 1958 and graduated with a BA(Hons) degree in English in 1961.
[6][7] She obtained a scholarship[4] which enabled her to pursue postgraduate studies at the School of Oriental & African Studies of the University of London in the United Kingdom where she obtained her PhD in Phonetics and Linguistics in 1965 with a dissertation entitled "The phonetics and phonology of the verbal piece in the Asante dialect of Twi".
She was joined by one other Ghanaian, Lawrence Boadi and some expatriates, Alan Duthie, Mrs. McCallien, Lindsay Criper and Helmut Truteneau.
[13] Florence Dolphyne has been the chairperson of the National Council for Women and Development in Ghana.
She has also been one of the commissioners who sat on the National Reconciliation Commission (2002 to 2004) which looked into the effects of military rule on people in Ghana.
[6] A special issue of the Ghana Journal of Linguistics dedicated to Professor Dolphyne appeared in 2018.
Her father was a Methodist minister from the Nzema people of Esiama in the Western Region of Ghana.