It was originally an affiliate college of the University of London,[7] which supervised its academic programs and awarded degrees.

[11] However, as part of a national educational reform program, the university's curriculum was expanded to provide more Technology-based and Vocational courses as well as Postgraduate Training.

[20] Here, two interlocking ram's horns (DWENINMENTOASO) have been used to symbolise strength and a call to pursue a path of integrity.

In the book commissioned by the University of Ghana, Professor Francis Agbodeka (1998) found that "Two members of the Legislative Council on their own volition worked on the question of securing funds for the project.

More significant, F. M. Bourret (1949), in almost a contemporaneous account, reported that the strong and united opinion expressed by Dr. Nanka-Bruce in a Radio Station Zoy address to the People of the Gold Coast in October 1947, "was largely instrumental in influencing the Secretary of State for the colonies" to finally give his consent in 1947, "for the establishment of a Gold Coast University College.

"[23] Significantly, the establishment of the University of Ghana, based on the Elliot Commission's Majority Report (of which Sir Arku Korsah of the Gold Coast was a member), was the culmination of immense work of several organizations, committees, institutions, and prominent individuals, at home and abroad.

Among some of the most prominent Ghanaians, members of organizations and civil society groups that campaigned for the establishment of the University of College of the Gold Coast/Ghana, included also Dr. Nanka-Bruce, Rev.

[25] She was elected as Chancellor and subsequently inducted into office on Wednesday, 1 August 2018, at a Special Congregation of the university held in the Great Hall.

The Legon Campus lies about 13 kilometers north-east of Accra, the capital of Ghana.

[20] The Korle-Bu Campus, headed by a Provost, houses the administration of the College of Health Sciences.

This campus is strategically located in the heart of the city and precisely at Adabraka and opposite the Ministry of Information.

This campus is part of the College of Education, and also offers Bachelor of Science in Business Administration.

[40] The university has Distance Education campuses in the various regions where it runs a variety of programs, including degree courses.

[52] The Graduate School of Nuclear and Allied Sciences is a post-graduate school established by Ghana Atomic Energy Commission (GAEC) in collaboration with the University of Ghana, with support from the International Atomic Energy Agency (IAEA) to enhance human resource development for the peaceful use of nuclear and related technologies in Ghana and Africa.

[65] Currently, various entry points into the campus require vehicle owners (typically staff and students) to obtain electronically scannable cards issued and authorized by the transport unit of the university.

The management of the university was labeled as 'insensitive' to the hardship caused by the COVID-19 pandemic after the school increased its facility user fees for 2020/21 academic year.

An investigative documentary was produced by former victims of the sexual harassment which was uploaded to YouTube.