The Florida Democratic Party holds neither of the state's U.S. Senate seats, and no statewide executive offices.

[3] John Milton led the party, and became governor of the state, during the Civil War era.

The presidential election in 2000 was decided by a margin of 537 votes out of approximately six million cast in the state, earning George W. Bush the presidency over Al Gore.

Since the passage of the Affordable Care Act, Florida Democrats have prioritized advocating Medicaid expansion in the state, a policy that would provide a federally subsidized healthcare plan to approximately one million Floridians.

[5][6] The current chairwoman of the Florida Democratic Party is former agriculture commissioner Nikki Fried, who succeeded former mayor of Miami Manny Diaz Sr. on February 25, 2023.

First elected in 2000, Nelson lost his bid for a fourth term in 2018 to Republican governor Rick Scott.