State Road 363 (SR 363) is a north–south route in the Big Bend region of Florida.

The road begins in St. Marks at Riverside Drive.

In Leon County and approaching Tallahassee, the road intersects US 319 and CR 259.

Just north of CR 259, SR 363 shares a brief concurrency with State Road 61 before veering west one block of SR 61 and continuing north in Tallahassee, parraeeling SR 61 one block to the west.

It crosses the CSX Railroad tracks in downtown Tallahassee on the M. S. Thomas Bridge.