Known locally as Orange Avenue, State Road 68 (SR 68) is a 4.5-mile-long east–west street in Fort Pierce, Florida.

The eastern terminus of SR 68 is at an intersection with North Fourth Street (US 1-SR 5); the roadway continues east a short distance towards Indian River Drive (County Road 707) in downtown Fort Pierce without state or county designation.

West of Kings Highway, Orange Avenue transitions into County Road 68, heading west for another 25.2 miles (40.6 km), maintaining the CR 68 designation as it crosses into Okeechobee County before ending at an intersection with US 441.

The rural nature of the western end of SR 68 is slowly giving way to urbanization, a trend throughout the Atlantic coast of the State of Florida, as orange groves are gradually being replaced by residential developments.

The historic western terminus of State Road 68 is about 42 miles (68 km) west of the current one.