County Road 615 (CR 615) begins here (albeit unsigned) and extends 10.1 miles (16.3 km) south to Port St. Lucie.

After winding its way through northern Port St. Lucie, St. James Drive ends at an intersection with Airoso Boulevard, with the CR 615 designation continuing south along Airoso Boulevard.

After intersections with Prima Vista Boulevard and Crosstown Parkway, CR 615 and Airoso Blvd.

finally reaches its southern terminus with Port St. Lucie Blvd.

No county route signage exists south of Edwards Road in Fort Pierce.