The company operates 47 bakeries producing bread, buns, rolls, snack cakes, pastries, and tortillas.

The DSD Segment handles fresh bread, buns, rolls, and snack cakes that are sold regionally through a network of independent distributors.

The European Bakers brand of frozen specialty bread and rolls are available nationally to retail in-store bakeries and foodservice customers.

[5] After acquiring bakeries in Florida, Alabama, and Georgia in the mid-to-late 1960s, the company in 1968 made an initial public offering, changed its name to Flowers Industries and began trading over-the-counter.

[3] Royal Cake Company was purchased in September 2005, and Flowers continued to operate the bakery in Winston-Salem, North Carolina.

Philadelphia-based snack cake baker Tastykake was acquired in 2011, expanding the company's markets into the mid-Atlantic region;[3][12] in 2012, it purchased Lepage Bakeries in Maine and acquired assets and licenses from Bimbo Bakeries for Sara Lee and Earthgrains brands in California and Oklahoma City.

[18] At the end of 2018, Flowers Foods bought Canyon Bakehouse, a privately held gluten-free bread company based in Johnstown, Colorado.