It is part of the Gainesville, Georgia metropolitan area, and lies on the shores of Lake Lanier.

Flowery Branch was established in 1874, one year after the Richmond and Danville Air-Line Railroad Railway System built a rail line through the city connecting Charlotte to Atlanta.

[4] Other sources claim the original name was Nattagasska ("Blossom Creek"), which long-term residents recall as an alternative nickname for the town.

[6][7] The historic Bowman-Pirkle House, built that same year, was originally located on the border of Flowery Branch and Buford.

[9] Ferdinand de Soto entered Hall County in March 1540 in transit between Stone Mountain and the Conasauga River.

Other resources located within the near vicinity of Flowery Branch include: asbestos, corundum, sand, and precious gems such as diamond and ruby.

The Atlanta Falcons football team's training camp has been located in Flowery Branch since the start of the 2005 season.

[21] King's Hawaiian operates a 116,000-sq ft bakery and distribution center in Flowery Branch.

[22] Wrigley's, a subsidiary of Mars, Incorporated, manufactures chewing gum products including Juicy Fruit, Orbit, Extra, and 5 in Flowery Branch.