[1][2] The bout was held on May 1, 2010, before a "sellout" crowd of 15,117 at the MGM Grand Garden Arena in Las Vegas, Nevada, United States.

[3] Boxing greats Muhammad Ali and Mike Tyson were among a long list of celebrities in attendance.

[3] The match was put together after Andre Berto pulled out of his scheduled January 30 unification bout against Mosley.

Shane Mosley was scheduled to face Andre Berto for a WBC and WBA Welterweight title unification bout on January 30, 2010.

However, the fight (and entire undercard) was called off on January 18, 2010, due to an earthquake in Haiti and Berto losing several family members in the disaster.

Negotiations for a proposed matchup between Mosley and Floyd Mayweather Jr. immediately began afterwards, ending with both sides agreeing to a set date of May 1, 2010, at the MGM Grand Garden Arena in Las Vegas, Nevada.

"[6][7] The earliest pre-fight hype came after Manny Pacquiao's fight with Joshua Clottey on March 13, 2010, when HBO aired a brief interview, confrontational-styled show entitled, "Face Off" with Max Kellerman hosting and leading the conversation.

During one installment of Mayweather-Mosley 24/7, Mayweather proclaimed himself the greatest boxer of all time, better than Sugar Ray Robinson and Muhammad Ali, and made light of Mosley's skill.

[8] On the night of the fight one commentator called it "the most highly anticipated welterweight matchup since Sugar Ray Leonard stopped Thomas Hearns in the 14th round in 1981.

"[8] Both Floyd Mayweather Jr. and Shane Mosley agreed to Olympic style drug testing for this fight, which included random sampling of blood and urine.

[10] In the middle rounds, he backed off on offense and Mayweather took advantage by picking up points with non-damaging hits.

[8] In the eighth, he became frustrated and received a referee warning after it appeared he tried to toss Mayweather to the ground in a wrestling-style move.

[15] With Richard Schaefer, the CEO of Golden Boy Promotions, who sponsored the fight saying he first thought that the buyrate would be around 3.5 to 4 million.