Fluvastatin

Fluvastatin is a member of the statin drug class, used to treat hypercholesterolemia and to prevent cardiovascular disease.

Myalgia (muscle pain), and rarely rhabdomyolysis, characteristic side effects for statins, can also occur.

[6] Fluvastatin works by blocking the liver enzyme HMG-CoA reductase, which facilitates an important step in cholesterol synthesis.

[1] In a Cochrane systematic review the dose-related magnitudes of fluvastatin on blood lipids was determined.

[1] Several cytochrome P450 enzymes (mainly CYP2C9, but also CYP3A4 and CYP2C8)[8] are involved in the metabolism of fluvastatin, which makes is less liable to interactions than most other statins.