[1] She acted as head of the civil service from 18 September 2019 till her swearing in on 4 March 2020 following the suspension of Winifred Ekanem Oyo-Ita.
[3] Yemi-Esan started her career at the Federal Ministry of Health in Nigeria, before she was promoted to the position of Director.
[6] On 18 September 2019, she was appointed as the acting head of civil service of the federation by the president of Nigeria, Muhammadu Buhari, replacing the suspended Winifred Ekanem Oyo-Ita.
[7] On 28 February 2020, she was made the permanent head of civil service of the federation and was sworn into office on 4 March 2020.
[8][9] In October 2022, a Nigerian national honour of Commander of the Order of the Federal Republic (CFR) was conferred on her by President Muhammadu Buhari.