Forced degradation

Usually conducted before final formulation, forced degradation uses external stresses to rapidly screen material stabilities.

Longer-term storage tests are usually used to measure similar properties when final formulations are involved because of the stringent FDA regulations.

There are a number of common stresses which are used to Chemical processes are often catalysed by the presence of acids and bases.

Temperature is often used in conjunction with other stresses to increase reaction rates.

Standard methodologies include: To demonstrate the specificity when developing stability indicating method.