Forsyth Medical Center is also active in a number of different clinical areas, including cancer diagnoses, stroke treatments and the delivery of babies.

Then, in 1912, after moving to a larger building due to overcrowding and insufficient funding, Winston voters approved bonds for a modern hospital to be constructed in the downtown area of what had become Winston-Salem.

[2] In 1959, voters approved a bond referendum to build a modern hospital on 77 acres (31 ha) along Silas Creek Parkway.

Twenty years later, in 1984, Carolina Medicorp Inc. (CMI), a non-profit organization, bought the deed for the hospital property from Forsyth County.

[citation needed] On February 11, 2014, Forsyth Medical Center reported to 18 patients who had undergone neurosurgery that they might have been exposed to Creutzfeldt–Jakob disease from improperly sterilized surgical instruments.