Fortitudo made the Italian league finals ten consecutive years (1997–2006).

Four consecutive finals losses were followed by Fortitudo's second league title in 2005, courtesy of a 3–1 win over Armani Jeans Milano in the finals series when instant replay upheld a Ruben Douglas buzzer beater in Game 4 of the championship series.

Fortitudo's first achievement in European competition was a FIBA Korać Cup final against Jugoplastika in 1977 in their maiden participation.

The 2006–07 season saw them change coaches three times as they finished thirteenth (out of eighteen), though they still qualified for the 2007–08 ULEB Cup.

After winning that league, Fortitudo was once again excluded from Serie A2 and the club's affiliation to the Italian Federation revoked.