[4] The Loyer family moved for John's National Basketball Association career with the Portland Trail Blazers, Philadelphia 76ers, New Jersey Nets and Detroit Pistons.
[5] Loyer had a very accomplished high school career, which placed his name in the MHSAA record book over 2 dozen times as of March 15, 2023[update].
[7] He also surpassed Dane Fife, his coaches son,[8] (2,287) for the Clarkston high school career scoring record on the same day that he scored 19 points in the second quarter of the 2018 MHSAA boys basketball Class A championship game to end his high school career with 2,325 points.
[10] Loyer was a Class A first-team all-state selection as a freshman by The Detroit News, which stated his averages were 16 points, 5.5 assists, 3 steals.
[15] On March 24, 2017, Loyer tallied 32 points in the MHSAA Class A semifinal 78–35 blowout against West Bloomfield at the Breslin Center.
[8] The next day, he posted 29 points, five rebounds and three assists to lead Clarkston to the MHSAA Class A championship with a 75–69 victory against a Grand Rapids Christian High School team that included Xavier Tillman Sr. and Duane Washington Jr. Tillman was a former Amateur Athletic Union (AAU) teammate of Loyer's and was 2017 Mr. Basketball of Michigan runner-up.
[6] According to Scout.com ratings at the beginning of his senior season, the Spartans had the third best recruiting class in 2018 with Marcus Bingham Jr., Gabe Brown, Aaron Henry, Loyer and Thomas Kithier.
[20] On February 27, 2018, Loyer had what seemed to be a season ending torn meniscus, but he sat out one game and was back on the court on March 7 playing through the injury,[1] since it was only a partial tear.
[5] On March 23, 2018, Loyer posted 42 points on 12–17 shooting in a MHSAA Class A 74-49 semifinal victory over De La Salle Collegiate High School.
[22][23] His record-setting high school career total of 634 free throws made surpassed a ten-year-old record of 629 set by Tekonsha's Dustin Orns.
[29] In the opening game of the Big Ten Tournament against Ohio State, Loyer scored 14 points off the bench, including three three-pointers to give MSU the lead.
[31] The team lost to Texas Tech in the Final Four of the 2019 NCAA Division I men's basketball tournament on April 6, 2019.
Loyer started in place of an injured Cassius Winston and posted a career-high and team-high 16 points, making all four of his three-point shots.
[38] On November 25, Loyer scored a career-high 20 points on six three-pointers in a starting role in a 83–67 win over Eastern Michigan at the Breslin Center with no fans attending.
After opening the season as the starter, he only started 7 games as he had difficulty consistently creating shots off the dribble and defending his position.
[48][49] On February 1 against St. Bonaventure, he extended his consecutive free throws made streak to 45, surpassing Steph Curry's school record of 41.
[50] Under head coach Bob McKillop, the Wildcats went 27–7 and was 2021–22 Atlantic 10 Conference men's basketball regular season.
[52] In the first round of the 2022 NCAA Division I men's basketball tournament, 10th-seeded Davidson was matched up against Loyer's former Spartan team.
"[10] Loyer also remained close with his 2018 Michigan State recruiting classmates Gabe Brown and Marcus Bingham Jr.[54] Davidson lost 74–73, with Loyer hitting a three-point shot to reduce the deficit to 2 points with 4.6 seconds remaining[55] and posting 12 points, 6 rebounds and 4 assists and going 5–5 from the free throw line.
[59] With Lee and Brajkovic departed and Matt McKillop taking over the head coaching job from his father, Loyer was the leader of the team for the 2022–23 Davidson Wildcats.
[70] The Davidson Wildcats 2023–24 Fact Book lists Loyer at 92.8% as the career free throw shooting percentage (minimum 200 made) above Cochran and Curry.
[71] According to the Atlantic 10 Conference 2019–20 Media Guide records, the A-10 career free throw percentage leader is Rick Suder of Duquesne Dukes men's basketball (342–390 87.69%, 1983–86, min 2.5 FT/game).