Together with Fotostiftung Schweiz [de], Fotomuseum Winterthur has been running a Center of Photography since autumn of 2003, with a bistro, a library, seminar rooms, a lounge, and a shop.

In June 2023, Fotomuseum Winterthur temporary closed the exhibition spaces at Grüzenstrasse 44, unrolling a redevelopment and expansion projects.

[3] The collection includes work by Nobuyoshi Araki,[4] Vanessa Beecroft,[5] Lewis Baltz, Daniele Buetti,[6] Larry Clark, Hans Danuser, William Eggleston, Nicolas Faure, Hans-Peter Feldmann,[7] Robert Frank, Nan Goldin, Paul Graham, Andreas Gursky, Roni Horn, Axel Hütte, Urs Lüthi, Boris Mikhailov, Arnold Odermatt, Gilles Peress, Liza May Post, Thomas Ruff, and Annelies Štrba.

This exhibition brought about thirty international artists reworking categories of representation to examine human-animal relations, including Katja Novitskova, Xiaoxiao Xu, Hiroshi Sugimoto, Erik Kessels, Filip Gilissen, Chris Marker and Charlotte Dumas, and is accompanied by a catalogue with illustrations and essays from artists and writers like Ana Teixeira Pinto and Slavoj Žižek.

[8] In 2015, Dr. Duncan Forbes established an exhibition programme that offers a unique perspective on photographic culture in the digital age.

This innovative platform is titled SITUATIONS and has featured works by Ryan Trecartin, Constant Dullaart, Jon Rafman, Vito Acconci and Mel Bochner.