The Four Seasons Hotel San Francisco at Embarcadero is a luxury hotel that occupies the top 11 floors of 48 story office tower of 345 California Center at 222 Sansome Street in the financial district of San Francisco, California.

Completed in 1986, the 345 California Center tower is the fifth-tallest in the city, at 211.8 m (695 ft).

Initially planned as condominiums, the twin towers of hotel were situated at 45-degree angles relative to the rest of the building, connected to each other by several glass skybridges that offer views of the San Francisco Bay Area.

[6] The hotel was originally set to reopen on May 1, 2020,[8] but the outbreak of the COVID-19 pandemic forced the opening to be postponed to October 1, 2020.

[9] As the pandemic quickly worsened, the newly opened hotel soon closed again, on December 20, 2020.