Fox Deportes features a diversified programming, including NFL pre and post-season games, MLB regular-season, All-Star Game, Divisional Series, National League Championship Series and World Series, the USGA's U.S. Open, NASCAR, Premier Boxing Champions, college football and soccer competitions including Liga MX and MLS.

The channel first launched in Southern California as La Cadena Deportiva Prime Ticket, a sister network to the original Prime Ticket regional sports network (the present day Bally Sports West), on November 1, 1993.

[7] The network also serves as the Spanish-language home to Major League Baseball, including the MLB All-Star Game, American and National League Championship Series (AL odd years, NL even years) and World Series, and World Baseball Classic.

On October 9, 2010, Fox Deportes picked up Spanish language rights to Formula One coverage, a contract which ran through 2012.

Beginning on October 15, 2024, the channel will air a Spanish language news program, Fox Noticias, produced by corporate sibling Fox News and initially hosted by Rachel Campos-Duffy, for one hour each weekday afternoon.