Serving the Alsace region from its headquarters in Strasbourg, France 3 Alsace produces regional news, sport, features and entertainment programming.

France 3 Alsace produces two daily region-wide news programmes - a 15 to 20-minute bulletin (midi-pile) at 1200 CET during Ici 12/13 and the main half-hour news at 1900 during Ici 19/20.

Two 10-minute sub-regional bulletins, Strasbourg-Deux Rives (serving Bas-Rhin) and France 3 Haute-Alsace (serving Haut-Rhin) are broadcast during Ici 19/20 at 1900 CET.

[2] On 5 January 2009, a 5-minute late night bulletin was introduced, forming part of Soir 3.

As well as the target coverage area of Alsace, France 3 Alsace also broadcasts to Basel in Switzerland and parts of Baden-Württemberg and Rhineland-Palatinate in Germany, counting to an overall potential audience of around 2.5 million people (including 1.8 million in Alsace).