His first wife, a daughter of the Earl of Westmorland, divorced him and married Arthur Paget as a result of her husband's many infidelities.

Talbot's marriage to Parker would prove more successful than his first one; they were married for thirty-one years.

She wrote several novels, including The Flying Burgomaster (1832), The Royal Intellectual Bazaar (1832), and The Man Without a Name (1852), and edited Dacre (1834).

[7] She lithographed the plates for Portraits of the Spruggins Family, another work to which she was mistakenly attributed authorship.

[8] Talbot died at Saltram on 6 December 1857 and was buried in the family vault at Plympton St Mary.